Eliminating the barriers to 3D cell culture

With exceptional cooling capabilities, precision syringe-based extrusion and an intuitive, easy-to-use desktop software in DNA Studio Core, the BIO ONE brings a new level of ease in the transition to 3D cell culture.

Designed for printing temperature-sensitive materials, the BIO ONE enables scientists to develop 3D models that replicate in vivo environments, contributing to accelerated discoveries.

Join in the paradigm shift that will accelerate discoveries across life science research.

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RT* - 0 °C

Printhead Temperature Range

* Room/Ambient temperature

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RT - 65 °C

Printbed temperature range

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0.1 μL

Volume step

Empowering researchers to take the step into another dimension

Conventional approaches such as traditional cell culture or animal testing have limitations, prompting the demand for more precise in vitro models in the life sciences. BIO ONE is an instrument that empowers researchers regardless of previous knowledge in constructing more physiologically relevant models, while reducing cost and ensuring more accurate data.

Cooling capabilities

Rapidly cool the BIO ONE printhead down to 0 °C and maintain the temperature throughout the print. With a novel design, ensure temperature stability till the tip of the nozzle from start to finish.

Material flexibility

The BIO ONE is designed to be an open material platform, meaning that users can load any material into a syringe and dispense it, including temperature-sensitive materials like collagen.

Precision extrusion

Enable total control over your print with the high-precision mechanical extrusion of the BIO ONE. The mechanism boasts an impressive 0.1 μL volume step.

Heated printbed

Extend construct stability and cell viability for heat-responsive materials through thermal crosslinking, using the built-in printbed heating ranging from RT – 65 °C.

Maximized reproducibility

Enable highly reproducible structures with limited print-to-print variation and human error, by both leveraging the precision and by saving your protocols to the software.

DNA Studio Core

Powered by DNA Studio Core, the BIO ONE has ease-of-use as its core principle, which makes it easier than ever to enter the world of 3D cell culture.

The BIO ONE Printhead

Precision in every print

The BIO ONE is equipped with a mechanically driven syringe-based printhead, ensuring precision and reproducibility in 3D model development. Mechanical extrusion offers superior accuracy when compared to pneumatic extrusion. 

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A 0.1 μL volume step and mechanical extrusion through a syringe for enhanced precision and reproducibility.

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Rapid and stable cooling of the entire printhead, maintaining any temperature from RT to 0 °C throughout the print.

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Excellent control and accurate printing of both low and high viscous biomaterial with consistent flow rates.

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Minimizing material waste by giving you the ability to precisely control the exact material volume of your print.

Powered by
DNA Studio Core

With DNA Studio Core, users have an easy-to-use desktop software which guides them through the entire bioprinting journey.

FEATURE HIGHLIGHTS

– Multiple printing modes, facilitating droplet or 3D construct printing
– Compatible with multiple file types
– User-friendly UI for an intuitive experience

Tissue Engineering

Engineering 3D tissue models

Bioprinting has become an essential tool in tissue engineering. With its user-friendly interface, the BIO ONE is the ideal stepping stone to start creating 3D tissue models. The easy creation of 3D tissue models such as cartilage or skin is a great boon in the research of a tissue’s regenerative properties, the study of wound healing, and developing in vitro alternatives to animals for cosmetic testing.

Material Science

Developing the next gen of biomaterials​

The open platform of the BIO ONE allows users to freely develop and readily use their own materials, without any workarounds or fees. Relying on non-proprietary syringes and nozzles, it is possible to print with any bioink. The software allows fine tuning of various printing parameters, including volume and flow, which means you can create protocols for most materials. This ensures the system can be used in multiple areas of material sciences, from bioink development and soft robotics to smart materials.

Drug Discovery

Better insights into the best candidates​​

With printing capability on up to 384-well plates, the BIO ONE enables researchers within the field of drug discovery to easily increase the number of replicates and gain a more accurate understanding of compound activity. This accelerates the drug discovery process by ensuring only the best candidates are carried along to clinical trials. Simply print an array of droplets to investigate drug delivery in easily reproducible in vitro models.