Ultrasonic homogenizers

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SCIENTZ08-IIIB Non-Contact Ultrasonic DNA Shearing System

The SCIENTZ08-IIIB Non-Contact Ultrasonic DNA Shearing System processes samples via isothermal and non-contact methods for shearing, homogenization and mixing. It enables sterile and ultra-trace sample disruption and can shear chromosomes directly through centrifuge tubes.

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Overview

Tailor-made for sample pretreatment in next-generation sequencing (NGS) DNA sample preparation and chromatin immunoprecipitation (ChIP) experiments, this system is ideal for laboratories handling high-throughput or valuable samples. It features high throughput, minimal sample loss and zero cross-contamination, and has become an indispensable standardized tool for ChIP and DNA shearing research platforms.

Working Principle

The SCIENTZ08-IIIB adopts a unique design with ultrasonic generators installed at the bottom of the water tank. Unlike traditional probe-type ultrasonic devices—where micro-flow and ultrasonic cavitation effects are limited to areas near the probe, resulting in high acoustic intensity per unit area but narrow ultrasonic radiation range—the non-contact design ensures the entire water tank is covered by ultrasonic waves. This delivers uniform and extensive ultrasonic distribution and reduces foam formation.

During operation, the system’s automatic continuous rotation of centrifuge tubes further optimizes ultrasonic energy distribution. Samples are placed in individually sealed centrifuge tubes, eliminating cross-contamination between samples, preventing aerosol transmission, and enhancing experimental biosafety.

Non-Contact Ultrasonic DNA Shearing System

Product Features

  • Digital Display: 7-inch touch screen for intuitive operation

  • Smart Storage: Stores up to 50 sets of experimental data

  • Adjustable Time: Ultrasonic time range: 0.1s to 199h 59min 59.9s

  • Adjustable Power: Power output steplessly adjustable from 1% to 100%

  • Wide Frequency Range: Auto-adaptive ultrasonic frequency from 20kHz to 400kHz

Application Fields

  • Cell disruption

  • Protein extraction

  • Inclusion body extraction

  • Micro-emulsification

  • DNA fragmentation

  • Chromatin immunoprecipitation (ChIP) and more