PhenoCycler Screened and Community Based Antibodies

Murine cancer models serve as a crucial bridge between basic research and clinical applications due to their ability to closely mimic human tumor biology and disease progression. Akoya Biosciences has developed a new 24-marker mouse I/O antibody panel for single cell spatial phenotyping of key immune cell types in the tumor microenvironment. This panel covers essential immune cell lineage and structural markers, enabling advanced research and comparative studies between mouse and human models to deepen our understanding of cancer biology.

KEY FEATURES

• Speed: Designed for the fastest spatial biology solution on the market
• Ready-to-use: Panel includes barcoded antibodies and corresponding reporters
• Flexible: Add additional markers to base panel using the custom conjugation kit

T Cell Markers
CD3e	T cell
CD4	Helper T cell
CD8	Cytotoxic T cell
FOXP3	Regulatory T cell
CD44	Activated T cell
CD45R/B220	Naive T cell
B Cell Markers
CD20	B cell

 

Structural, Proliferation and Tumor Markers
Vimentin	Mesenchymal cells, epithelialmesenchymal transition (EMT)
Col1A1	Extracellular matrix
Caveolin	Integral membrane protein
PanCK	Epithelial cells, tumor marker
Ki67	Proliferation marker
Other Cell Type Markers
CD31	Endothelial cells
CD36	Adipocyte progenitors
Ter119	Erythroid cells

 

Macrophage Markers
CD68	Macrophage
CD206	M2 macrophage
F4/80	Macrophage
Immune Cell Markers
CD11c	Panleukocyte
Ly6g	Peripheral neutrophils, monocytes and granulocytes
FCRγ	Multiple immune cell types
CD45	Nucleated hematopoietic cells
Iba1	Microglia
S100A9	Myeloid differentiation