Magnetofection

Overview

CombiMag Transfection Reagent is the only existing reagent based on the use of magnetic nanoparticles (Magnetofection™), for improving your transfection reagent efficiency. It has been designed to be employed in association with any commercial transfection reagent and can be used with all types of nucleic acids. It has been successfully tested on a broad range of primary cells, hard-to-transfect cells and cell lines. Its efficiency has been reported in many publications. CombiMag allows creating your own optimal delivery system with at least 30%  transfection efficiency enhancement. 

• Ideal to enhance any transfection reagent efficiency without changing your protocol /cells
• Perfect for primary cells and hard-to-transfect cells
• Increase any transfection reagent efficiency
• Non toxic
• Compatible with and without serum
• Simple, rapid and easy-to-use
• For all types of nucleic acids

Sizes:

• 100 µL: 100 transfections with 1 µg of DNA
• 200 µL: 200 transfections with 1 µg of DNA
• 1000 µL: 1000 transfections with 1 µg of DNA
• #KC30200: Starting Kit with Super Magnetic Plate + 100 µL of CombiMag, PolyMag, PolyMag Neo
• #KC30296 : Starting kit with plate 96 magnets + 100 µL of CombiMag, PolyMag, PolyMag Neo
• #KC30400 : Super starting kit with Super Magnetic Plate + 200µl of Silencemag, 100 µL of CombiMag, PolyMag, PolyMag Neo
• #KC30496 : Super starting kit with plate 96 magnets + 200µl of Silencemag, 100 µL of CombiMag, PolyMag, PolyMag Neo

Storage: +4°C

Shipping conditions: Room temperature

• This reagent needs to be used with a magnetic plate

Applications

• Boost all commercial transfection reagents.
• Ideal for mammalian cells: Cell lines, primary & hard to transfect cells.
• Perfect for all transfections applications:
  • Transient or stable transfection
  • gene silencing
  • in presence or absence of serum
• Suitable for all nucleic acids: DNA, oligonucleotides, mRNA, siRNA, shRNA...

RECOMMENDED FOR: enhancing any transfection reagent efficiency of primary and hard-to-transfect cells 

Results

Figure 1:Transfection of various cell lines using a commercial transfection reagent alone or in combination with CombiMag.

Figure 2: Luciferase expression in primary rabbit articular chondrocytes transfected with various commercial reagents without or with CombiMag. We are grateful to Dr. U. Schillinger (Technical University, Munich) for kindly providing these data.